Professor GE Jun received his B.Sc. degree in polymer science at Department of Chemical Engineering, Tsinghua University in 2004 and his Ph.D. degree in chemical engineering at Department of Chemical Engineering, Tsinghua University in 2009. From 2009 to 2012, as a postdoctoral scholar, he worked in Prof. Richard N. Zare's lab at the Department of Chemistry, Stanford University, U.S.A. He has worked at the Department of Chemical Engineering, Tsinghua University since 2012 and was promoted as an associate professor in the same year. His current research interests include biochemical engineering, biocatalysis, biomedicine and biosensing. Dr. Ge has published over 100 SCI papers and his research has been supported by several national research projects. Dr. Ge was awarded as "World 35 Top Innovators Under 35"by MIT Technology Review (TR35).

2000~2004 B.Sc, Department of Chemical Engineering, Tsinghua University

2004~2009 Ph.D, Department of Chemical Engineering, Tsinghua University

2009~2012 Postdoctoral Scholar, Department of Chemistry, Stanford University

2012 Assistant Professor, Department of Chemical Engineering, Tsinghua University

2012~2020 Associate Professor, Department of Chemical Engineering, Tsinghua University

2020~present Professor, Department of Chemical Engineering, Tsinghua University

enzymatic catalysis, nanobiotechnology, enzyme immobilization, synthetic biology, biomedicine

1. Yuan, X. #; Wu, X. #*; Xiong, J.; Yan, B.; Gao, R.; Liu, S.; Zong, M.; Ge, J. *; Lou, W. * Hydrolase mimic via second coordination sphere engineering in metal-organic frameworks for environmental remediation. Nature Communications 2023, 14(1), 5974.

2. Cao, Y. #; Chen, Z. #; Li, P.; Ozden, A.; Ou, P.; Ni, W.; Abed J.; Shirzadi, E.; Zhang, J.; Sinton D.; Ge, J. *; Sargent, E. * Surface hydroxide promotes CO2 electrolysis to ethylene in acidic conditions. Nature Communications 2023, 14(1), 2387.

3. Li, X.; Hu, X.; Qiao, Y.; Lu, T.; Bai, Y.; Xiong, J.; Li, X.; Gou, Q.; Ge, J. * Enzyme-bimetallic hybrid catalyst for one-pot chemoenzymatic reactions. Chemical Engineering Journal 2023, 452, 139356.

4. Li, X.; Cao, Y.; Xiong, J.; Li, J.; Xiao, H. *; Li, X.; Gou, Q.; Ge, J. * Enzyme-metal-single-atom hybrid catalysts for one-pot chemoenzymatic reactions. Chinese Journal of Catalysis 2023, 44, 139-145.

5. Liu, Y.; Ge, J. * Into the unknown: Micro/nanomotors propelled by biocatalysis based on metal-organic frameworks. Chem Catalysis 2022, 2(10), 2458-2470.

6. Yang, J. #; Lin, C. #; Feng, Y. #; Wang, C.; Ge, J. *; Lu, Y. * Chemical-triggered artificial cell based on metal-organic framework. Chemical Engineering Journal 2022, 450, 138480.

7. Xiong, J. #; Cao, Y. #; Zhao, H.; Chen, J.; Cai, X.; Li, X.; Liu Y., Xiao, H.; Ge, J. * Cooperative Antibacterial Enzyme-Ag-Polymer Nanocomposites. ACS nano 2022, 16(11), 19013-19024.

8. Bai, Y.; Luan, P.; Bai, Y.; Zare, R. N.*; Ge, J.* Enzyme-photo-coupled catalysis in gas-sprayed microdroplets. Chemical Science, 2022, 13, 8341-8348

9. Zhang, Y.; Xu, L.; Ge, J.* Multienzyme system in amorphous metal-organic frameworks for intracellular lactate detection. Nano Letters 2022, 22(12), 5029-5036.

10. Cao, Y.; Qiao, Y.; Cui, S.; Ge J.* Origin of metal cluster tuning enzyme activity at the bio-nano interface. JACS Au 2022, 2(4), 961-971.

11. Li, X.; Fu, C.; Luo, L.; Ge, J.* Design of enzyme-metal hybrid catalysts for organic synthesis. Cell Reports Physical Science 2022, 3, 100742.

12. Li, X. #; Cao, Y. #; Luo, K.; Zhang, L.*; Bai, Y.; Xiong, J.; Zare, R. N.*; Ge, J.* Cooperative catalysis by a single-atom enzyme-metal complex. Nature Communications 2022, 13, 2189.

13. Feng, Y.#; Cao, X.#; Zhang, L.*; Li, Y.; Cui, S.; Bai, Y.; Chen, K.; Ge, J.* Defect engineering of enzyme-embedded metal–organic frameworks for smart cargo release. Chemical Engineering Journal 2022, 439, 135736.

14. Cao, Y.; Ge, J.* Hybrid enzyme catalysts synthesized by a de novo approach for expanding biocatalysis. Chinese Journal of Catalysis 2021, 42, 1625-1633.

15. Cao, Y.; Li, X.; Ge, J.* Enzyme catalyst engineering toward the integration of biocatalysis and chemocatalysis. Trends in Biotechnology 2021, 39, 1173-1183.

16. Li, X.; Cao, X.; Xiong, J.; Ge, J.* Enzyme-metal hybrid catalysts for chemoenzymatic reactions. Small 2020, 16, 1902751.

17. Hu, C.#; Bai, Y.#; Hou, M.; Wang, Y.; Wang, L.; Cao, X.; Chan, C.-W.; Sun, H.; Li, W.; Ge, J.*; Ren, K.* Defect-induced activity enhancement of enzyme-encapsulated metal-organic frameworks revealed in microfluidic gradient mixing synthesis. Science Advances 2020, 6(5), eaax5785.

18. Wu, X.#; Yue, H.#; Zhang, Y.#; Gao, X.; Li, X.; Wang, L.; Cao, Y.; Hou, M.; An, H.; Gu, H.; Zhang, L.*; Li, S.*; Lou, W.; Ma, J.; Lin, H.; Fu, Y.; Wei, W.*; Zare, R. N.; Ge, J.* Packaging and delivering enzymes by amorphous metal-organic frameworks. Nature Communications 2019, 10, 5165.

19. Li, X. #; Cao, Y. #; Luo, K. #; Sun, Y.; Xiong, J.; Wang, L.; Liu, Z.; Li, J.; Ma, J.; Ge, J.*; Xiao, H.*; Zare, R. N.* Highly active enzyme-metal nanohybrids synthesized in protein-polymer conjugates. Nature Catalysis 2019, 2, 718-725.

20. Cao, Y.#; Li, X.#; Xiong, J.; Wang, L.; Yan, L.*; Ge, J.* Investigating the origin of high efficiency in confined multienzyme catalysis. Nanoscale 2019, 11, 22108-22117.

21. Wu, X.; Yang, C.; Ge, J.* Green synthesis of enzyme/metal-organic framework composites with high stability in protein denaturing solvents. Bioresources and Bioprocessing 2017, 4, 24.

22. Wu, X.; Hou, M.; Ge, J.* Metal-organic frameworks and inorganic nanoflowers: a type of emerging inorganic crystal nanocarriers for enzyme immobilization. Catalysis Science & Technology 2015, 5, 5077-5085.

23. Zhang, Y.; Ge, J.*; Liu, Z.* Enhanced activity of immobilized or chemically modified enzymes. ACS Catalysis 2015, 5, 4503-4513.

24. Wu, X.; Ge, J.*; Yang C.; Hou, M.; Liu, Z. Facile synthesis of multiple enzyme-containing metal-organic frameworks in a biomolecule-friendly environment. Chemical Communications 2015, 51, 13408-13411.

25. Wu, X.; Ge, J.*; Zhu, J.; Zhang, Y.; Yong, Y.; Liu, Z.* A general method for synthesizing enzyme-polymer conjugates in reverse emulsions using Pluronic as a reactive surfactant. Chemical Communications 2015, 51, 9674-9677.

26. Lyu, F.; Zhang, Y.; Zare, R. N.; Ge, J.*; Liu, Z.* One-pot synthesis of protein-embedded metal-organic frameworks with enhanced biological activities. Nano Letters 2014, 14, 5761-5765.

27. Li, Z.; Zhang, Y.; Su, Y.; Ouyang, P.; Ge, J.*; Liu, Z.* Spatial co-localization of multi-enzymes by inorganic nanocrystal-protein complexes. Chemical Communications 2014, 50, 12465-12468.

28. Zhang, Y.; Lyu, F.; Ge, J.*; Liu, Z.* Ink-jet printing an optimal multi-enzyme system. Chemical Communications 2014, 50, 12919-12922.

29. Zhu, J.; Zhang, Y.; Lu, D.; Zare, R. N.; Ge, J.*; Liu, Z.* Temperature-responsive enzyme-polymer nanoconjugates with enhanced catalytic activities in organic media. Chemical Communications 2013, 49, 6090-6092.

30. Ge, J.#; Neofytou, E.#; Lei, J.; Beygui, R. E.; Zare, R. N.* Protein-polymer hybrid nanoparticles for drug delivery. Small 2012, 8, 3573-3578.

31. Ge, J.#; Lei, J.#; Zare, R. N.* Protein-inorganic hybrid nanoflowers. Nature Nanotechnology 2012, 7, 428-432.

32. Ge, J.#; Neofytou, E.#; Cahill, III, T. J.; Beygui, R. E.; Zare, R. N.* Drug release from electric-field-responsive nanoparticles. ACS Nano 2012, 6, 227-233.

33. Ge, J.; Lei, J. D.; Zare, R. N.* Bovine serum albumin-poly(methyl methacrylate) nanoparticles: an example of frustrated phase separation. Nano Letters 2011, 11, 2551-2554.

34. Yan, M.; Ge, J.; Liu, Z.*; Ouyang, P. Encapsulation of single enzyme in nanogel with enhanced biocatalytic activity and stability. Journal of the American Chemical Society 2006, 128, 11008-11009.

2015 MIT “Technology Review” Word 35 Innovators Under 35 (TR 35)

2016 Excellent Young Scholars, National Science Foundation of China

2017 Yangtze River Scholars Young Professor

2017 Tsinghua University Liu Shuli Award for Education

2018 Distinguished Young Scholars, Beijing National Science Foundation

2020 Advisor for Excellent Doctor Degree Dissertation of Tsinghua University

2021 GACCE Future Chemical Engineering Scholar

2024 Outstanding Young Scholars, National Science Foundation of China