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杜伟 副教授
电话: 010-62772130 地址:清华大学工物馆 邮件: duwei@tsinghua.edu.cn |
一直致力于酶促油脂制备生物能源、生物基化学品过程中的应用基础研究,解析非水相酶催化过程中酶活性和选择性的影响机理,开发高效酶催化剂、先进转化技术和装备,并促进其工业化应用(酶法制备生物柴油技术已在万吨级装置上实现产业化)。发表SCI论文60余篇, 2014-2019年连续六年在Elsevier发布的中国高被引学者(Most Cited Chinese Researchers)榜单中入选。获得中国发明专利授权24项,国际专利申请在美国、巴西等20余个国家授权。先后获得2016年度中国石油化学工业联合会“科技发明一等奖”(第一完成人)、2016年度全球可再生能源领域最具投资价值领先技术“蓝天奖”(第一完成人)、2015年度日内瓦国际发明专利金奖(第二完成人)、国石油和化学工业协会“2014年度青年科技突出贡献奖”和中国化工学会“2015年度侯德榜化工科技青年奖”。
● 教育与工作经历
1993~1997 华南理工大学生物工程系 本科
1997~2002 华南理工大学生物工程系 博士
2002~2004 清华大学化学工程系 博士后
2004~2006 清华大学化学工程系 讲师
2007~至今 清华大学化学工程系 副教授
● 研究领域
非水相酶催化;生物柴油;微生物油脂;可再生油脂生物转化;结构脂制备与构效研究
● 开设课程及编写教材
本科生《工业微生物及其应用》
本科生《化工实验2》
研究生《化学工程伦理》
● 主要学术任职
2018年~至今 中国可再生能源学会 会员
2017年~至今 中国化学学会 会员
● 代表性论文/专利/著作
1)Zitian Wang, Lingmei Dai, Dehua Liu,Hongjuan Liu, Wei Du. Kinetics and Mechanism of Solvent Influence on the Lipase-Catalyzed 1,3-Diolein Synthesis. ACS Omega, 2020, 5(38): 24708-24716
2)Yingli Hu, Lingmei Dai, Dehua Liu, Du Wei.Hydrophobic pore space constituted in macroporous ZIF-8 for lipase immobilization greatly improving lipase catalytic performance in biodiesel preparation. Biotechnology for Biofuels. 2020, 13(1): DOI: 10.1186/s13068-020-01724-w
3)Dingyaw Kuan, Lingmei Dai, Dehua Liu, Wei Du, Hongjuan Liu. A novel clean process for the combined production of fatty acid ethyl esters (FAEEs) and the ethyl ester of polyunsaturated fatty acids (PUFAs) from microalgae oils. Renewable Energy, 2019, 143:772-778
4)Yingli Hu, Lingmei Dai, Dehua Liu, Wei Du. Rationally Designing Hydrophobic UiO-66 Support for the Enhanced Enzymatic Performance of Immobilized Lipase. Green Chemistry 2018, 20: 4500-4506
5)Xingguo Tian, Xin Chen, Lingmei Dai, Dehua Liu, Wei Du. Improved lipase-catalyzed methanolysis for biodiesel production by combining in-situ removal of by-product glycerol, fuel, 2018, 232: 45-50
6)Gaojian Ma, Lingmei Dai, Dehua Liu, Wei Du. Lipase-Mediated Selective Methanolysis of Fish Oil for Biodiesel Production and Polyunsaturated Fatty Acid Enrichment. Energy & Fuels 2018, 32: 7630-763
7)Liangliang Lv, Lingmei Dai, Wei Du*, Dehua Liu*. Effect of water on lipase NS81006-catalyzed alcoholysis for biodiesel production. Process Biochemistry, 2017, 58:239-244
8)Songmei Wang, Johnny Zhu, Lingmei Dai, Xuebing Zhao, Dehua Liu, Wei Du. A novel process on lipid extraction from microalgae for biodiesel production, Energy, 2016,115: 963–968
9)Xingguo Tian, Lingmei Dai, Minsheng Liu, Dehua Liu, Wei Du,Hong Wu. Lipase-catalyzed methanolysis of microalgae oil for biodiesel production and PUFAs concentration, Catalysis Communications, 2016, 84:44-47
10)Zitian Wang, Wei Du,Lingmei Dai, Dehua Liu. Study on Lipozyme TL IM-catalyzed esterification of oleic acid and glycerol for 1,3-diolein preparation, Journal of Molecular Catalysis B Enzymatic, 2016, 127:11-17
11)Renwang Li, Wei Du, Dianlan Lu, Lingmei Dai, Dehua Liu. Study on the enzyme's 1,3-positional specificity during lipozyme TL-mediated biodiesel production, Rsc Advances, 2015, 5:62460-62468
12)Yang Li, Wei Du, Dehua Liu. Efficient biodiesel production from phospholipids-containing oil: Synchronous catalysis with phospholipase and lipase, Biochemical Engineering Journal, 2014, 94: 45–49
13)Yang Li, Wei Du, Dehua Liu. Free lipase-catalyzed biodiesel production from phospholipids-containing oils, Biomass & Bioenergy, 2014, 71:162-169
14)Feng Qi, Yuki Kitahara, Zitian Wang, Xuebing Zhao, Wei Du, Dehua Liu. Novel mutant strains of Rhodosporidiumtoruloides by plasma mutagenesis approach and their tolerance for inhibitors in lignocellulosichydrolyzate, Journal of Chemical Technology and Biotechnology, 2014,89: 735-740
15)Hongjie Ren , Yang Li, Wei Du, Dehua Liu. Free lipase-catalyzed esterification of oleic acid for fatty acid ethyl ester preparation with response surface optimization, Journal of the American Oil Chemists' Society, 2013, 90(1):73-79