主要从事生物化工领域的教学和研究工作，主要内容包括蛋白质构象转换调控及其在蛋白质折叠和分离中的应用，纳米酶制剂及其在工业催化中的应用以及土壤生物修复技术等。发表论文190余篇，其中SCI收录 120余篇，专利授权10项。已培养研究生逾50名，其中全国优秀百篇博士论文1人。先后获清华大学研究生良师益友奖（2004，2018，2020），获得全国高等学校优秀骨干教师奖（2002），教育部新世纪优秀人才支持计划（2004），国务院政府特殊津贴（2007），宝钢优秀教师（2016）。

●  教育与工作经历

1982~1987     清华大学化学工程系    本科

1987~1989     清华大学化学工程系    硕士

1989~1993     清华大学化学工程系    博士

1993~1994     日本东京工业大学      访问学者

1993~1996     清华大学化学工程系    讲师

1996~1998     清华大学化学工程系    副教授

1998~至今      清华大学化学工程系    教授

●  研究领域

蛋白质构象转换调控及其在蛋白质折叠和分离中的应用；纳米酶制剂及其在工业催化中的应用；土壤生物修复。

●  开设课程及编写教材

清华大学本科生《分子设计与化学工程》

清华大学研究生《生物分离工程》（英文）

●  主要学术任职

2018年~至今   教育部化工类教学指导委员会  委员

2021年~至今   国务院学位办化学工程与技术分委员委员

2012年~至今   中国化工学会生物化工专业委员会  副主任

2012年~至今   工业生物催化教育部重点实验室  主任 

●  代表性论文/专利/著作

1.Weina Xu, Zhongwang Fu, Gong Chen, Zheyu Wang, Yupei Jan, Yifei Zhang, Guoqiang Jiang, Diannan Lu, Jianzhong Wu and Zheng Liu*, Graphene oxide enabled long-term enzymatic transesterification in an anhydrous gas flux, Nat. Commun., 2019, 10, 2684.

2.Zhongwang Fu, Weina Xu, Gong Chen, Zheyu Wang, Diannan Lu*, Jianzhong Wu*, Zheng Liu*, Molecular dynamics simulations reveal how graphene oxide stabilizes and activates lipase in an anhydrous gas, Phys.Chem.Chem.Phys., 2019, 21, 25425-25430.

3.Gong Chen, Weina Xu, Diannan Lu*, Jianzhong Wu* and Zheng Liu*, Markov-state model for CO2 binding with carbonic anhydrase under confinement, J. Chem. Phys., 2018, 148, 035101.

4.Weina Xu, Zheyu Wang, Gong Chen, Zhongwang Fu, Guoqiang Jiang, Jian Chen, Jianzhong Wu and Zheng Liu*, Accelerating CO2 Absorption in Aqueous Amine Solutions at High Temperature with Carbonic Anhydrase in Magnetic Nanogels, Catal. Lett., 2018, 148, 1827-1833.

5.Zheyu Wang, Junqian Wang, Gong Chen, Weina Xu, Zhongwang Fu, Guoqiang Jiang, Jianzhong Wu and Zheng Liu*, Polyelectrolytes tailored enzyme cascades with enhanced stability and activity for one-pot synthesis, ChemCatChem, 2018, 10, 5391-5396.

6.You Yong, Rui Su, Xuerun Liu, Weina Xu, Yifei Zhang, Rui Wang, Pingkai Ouyang, Jianzhong Wu, Jun Ge and Zheng Liu*, Lectin corona enhances enzymatic catalysis on the surface of magnetic nanoparticles, Biochem. Eng. J., 2018, 129, 26-32.

7.Zheyu Wang, Weina Xu, Zhongwang Fu, Guoqiang Jiang, Jianzhong Wu and Zheng Liu*, Pluronic-Conjugated Enzyme Cascade for In Situ Oxidation in Biphasic Media, ChemCatChem, 2018, 10, 2003-2008.

8.Gong Chen, Diannan Lu*, Jianzhong Wu and Zheng Liu*, Detachment of HCO3- from the Active Site of Carbonic Anhydrase: Molecular Dynamics Simulation and Machine Learning, J. Phys. Chem. C, 2018, 122, 20539-20549.

9.Gong Chen, Xian Kong, Diannan Lu, * Jianzhong Wu* and Zheng Liu*，Kinetics of CO2 diffusion in human carbonic anhydrase: a study using molecular dynamics simulations and the Markov-state model, Phys. Chem. Chem. Phys., 2017, 19, 11690-11697.

10.Weina Xu, You Yong, Zheyu Wang, Guoqiang Jiang, Jianzhong Wu and Zheng Liu*, Concanavalin A Coated Activated Carbon for High Performance Enzymatic Catalysis, ACS. Sustain. Chem. Eng., 2016, 5, 90-96.

11.Yifei Zhang, You Yong, Jun Ge and Zheng Liu*, Lectin agglutinated multienzyme catalyst with enhanced substrate affinity and activity, ACS. Catal., 2016, 6, 3789-3795.

12.Xian Kong, Diannan Lu, Jianzhong Wu and Zheng Liu*, Spreading of a Unilamellar Liposome on Charged Substrates: A Coarse-Grained Molecular Simulation, Langmuir, 2016, 32, 3785-3793.

13.Xiaoling Wu, Jun Ge,* Jingying Zhu, Yifei Zhang, You Yong and Zheng Liu*，A general method for synthesizing enzyme–polymer conjugates in reverse emulsions using Pluronic as a reactive surfactant，Chem. Commun., 2015, 51, 9674-9677.

14.Fengjiao Lyu, Yifei Zhang, Richard N. Zare, Jun Ge* and Zheng Liu*, One-Pot Synthesis of Protein-Embedded Metal−Organic Frameworks with Enhanced Biological Activities, Nano Letters, 2014, 14: 5761-5765.

15.Yifei Zhang, Fengjiao Lyu, Jun Ge* and Zheng Liu*, Ink-jet printing an optimal multi-enzyme system, Chem, Commun., 2014, 50: 12919-12922.

16.Zhixian Li, Yifei Zhang, Yechao Su, Pingkai Ouyang, Jun Ge* and Zheng Liu*, Spatial co-localization of multi-enzymes by inorganic nanocrystal–protein complexes, Chem Commun., 2014, 50: 12465-12468.

17.Xian Kong, Zhixian Li, Diannan Lu,* Zheng Liu* and Jianzhong Wu*, Multiscale simulation of surfactant–aquaporin complex formation and water permeability, RSC Advances, 2014, 4, 37592–37599.

18.Yifei Zhang, Qile Chen, Jun Ge* and Zheng Liu*, Controlled display of enzyme activity with a stretchable hydrogel, Chem Commun, 2013, 49:9815-7

19.Jingying Zhu, YifeiZhang, Diannan Lu, RN Zare, Jun Ge* and Zheng Liu*, Temperature-responsive enzyme-polymer nanoconjugates with enhanced catalytic activities in organic media, Chem Commun, 2013, 49, 6090-6092.

20.Rui Wang, Yifei Zhang, JinhaiHuang, Diannan Lu, Jun Ge*, Zheng Liu*, Substrate imprinted lipase nanogel for one-step synthesis of chloramphenicol palmitate, Green Chemistry, 2013, 15:1155-1158.

●  学术荣誉与奖励 

2016年         宝钢全国优秀教师特等奖提名奖

2008年         全国优秀博士论文指导教师

2007年         国务院政府特殊津贴

2004年         教育部新世纪优秀人才计划

2004年         北京市优秀教师

2002年         高等学校优秀骨干教师