清华化工论坛第六十讲将于10月18日15:30在英士楼201会议室举行，欢迎各位老师参加！

报告题目：Catalysis Driven by “Nanoenzymes” or Functional Assemblies in Nanoscale or Supramolecular Structures

演讲人：Professor Itamar Willner Institute of Chemistry, The Hebrew University of Jerusalem, Israel

报告时间：10月18日15:30

报告地点：英士楼201会议室

Catalysis Driven by “Nanoenzymes” or Functional Assemblies in Nanoscale or Supramolecular Structures

Itamar Willner

Institute of Chemistry, The Hebrew University of Jerusalem, 91904 Jerusalem, Israel

The introduction of new catalysts and the control over the switchable and programmed functions of catalytic systems are key challenges in chemistry. Two new methods to develop catalysts will be introduced: (i) The application of heterogeneous nanoparticles as “nanoenzymes” that catalyze different transformations will be described. The surface modification of the nanoenzymes leading to switchable catalytic functions of nanoenzymes will be addressed. (ii) Catalytic units are conjugated to aptamer recognition sequences to yield a new class of DNA-based catalysts termed “nucleoapzymes”. Their application to catalyze different chemical transformations will be discussed. In addition, the control over the switchable functions of catalysts will be addressed by introducing two different concepts: (a) The use of origami DNA scaffolds for switchable catalysis. This will include the stimuli-triggered reconfiguration of origami-dimers that act as a switchable scaffold for the selective, dictated, operation of DNAzymes. (b) The application of DNA-based constitutional dynamic networks (CDNs) for programmed catalysis. The implications of these systems for the “evolution of life” will be presented.

Curriculum Vitae - Professor Itamar Willner

(Synopsis)

Address: Institute of Chemistry

The Hebrew University of Jerusalem

Jerusalem 91904, Israel

Fax: 972-2-6527715

Tel: 972-2-6585272

E-mail:willnea@vms.huji.ac.il

Homepage: http://chem.ch.huji.ac.il/willner/

Academic Background:

1974-1978 Ph.D. Thesis, Physical Organic Chemistry, The Hebrew University of Jerusalem

1978-1980 Post-doctoral fellow, U.C. Berkeley, Physical Chemistry

1980-1981 Staff Scientist and Adjunct Assistant Professor, U.C. Berkeley

1981-1983 Senior Lecturer, Hebrew University of Jerusalem

1983-1986 Associate Professor, Hebrew University of Jerusalem

1986- Professor, Hebrew University of Jerusalem

Research Activities:

Supramolecular Chemistry, Nanotechnology, Nanobiotechnology, Molecular Self-Assembly, Molecular and Biomolecular Machines, Molecular and Biomolecular Electronics, Sensors and Biosensors, Electronics and Photophysics of Nanoparticles and Quantum Dots,Functionalized Monolayers, Molecular Optoelectronics, Optobioelectronics, Photocatalysis, Photoinduced Electron Transfer, Artificial Photosynthesis, Sensors and Biosensors, Biofuel Cells.

Awards and Honors:

Bergmann Award - 1986

Honorary Professor, Osaka University, Osaka, Japan - 1991

Kolthoff Award - 1993

AAAS (American Association for the Advancement of Science) Fellow - 1996

Sandoz-Novartis Award - 1997

The Kaye Innovations Award – 1998, 2004

Max Planck Research Award for International Cooperation – 1998

Israel Chemical Society Award – 2001

Israel Prizein Chemistry– 2002

Member of The Israel Academy of Sciences – 2002

The Klachky Family Prize for the Advancement of the Frontiers of Science – 2003

Member of the European Academy of Sciences and Arts - 2004

Honorary Guest Professorship, Tsinghua University, Beijing, China – 2005

Honorary Professor, East China University of Science and Technology, Shanghai, China – 2007

Rothschild Prize in Chemistry – 2008

EMET Prize in Chemistry (under the auspices of the Prime Minister of Israel) – 2008

Fellow of the Royal Society of Chemistry (FRSC), UK – 2009

Member of the German National Academy of Sciences Leopoldina – 2009

ACS Nano Lectureship Award – 2013

Thomson Reuters – Highly Cited Researcher and listed in the World’s Most Influential Scientific Minds – 2014, 2015, 2016, 2017 and 2018

Gold Medal of the Israel Chemical Society – 2016

Publications:

Over 775 papers and 30 patents.

h-index (Web of Science): 128

h-index (Google Scholar): 148