赵雪冰,博士,副教授,博士生导师

 

清华大学化学工程系应用化学研究所

 

地址:清华大学英士楼314

电话:+86-10-62772130-111

传真:+86-10-62772130-117

邮箱:zhaoxb@mail.tsinghua.edu.cn

 

招生:本课题组每年招收1-2名博士生,1-2名硕士生,欢迎推免和报考!

 

 

教育经历

2004.09-2009.07       清华大学化学工程系化学工程与技术,博士

2000.09-2004.07       清华大学化学工程系化学工程与工艺专业,学士

 

工作经历

2011.07  至今  清华大学化学工程系助理研究员,硕士生导师;副教授(特别研究员),博士生导师

2014.02-2015.03  美国威斯康辛大学麦迪逊校区,博士后

2009.07-2011.06  清华大学化学工程系,博士后

2008.05-2008.07  荷兰阿姆斯特丹壳牌公司研发中心,研究助理

 

获得奖励

2017 侯德榜化工科技青年奖

2016 石油和化学工业联合会科技进步一等奖;2016年生物工程学报优秀论文(通讯作者)

20122013 清华大学化工系优秀本科论文(指导教师)

20122014 清华大学实验技术成果奖II等)

 

学术兼职

n  Journal of Enzyme Research期刊主编(Editor-in-Chief)(2012-2016

n  BioEnergy Research期刊的客座编辑(Guest Editor)(2011

n  International Journal of Polymer Science期刊的客座编辑(Guest Editor)(2017

n  International Journal of Biochemistry and Molecular Biology Research编委

n  Trends in Biotechnology, Bioresource TechnologyBiotechnology for biofuelsGreen Chemistry, Energy & Fuel80余个国际期刊论文评审人

n  智利国家科技发展基金会20102012年普通研究基金的外籍评审人。

 

研究工作

木质纤维素化学和生物转化生产生物燃料和化学品

主要从事生物质化学和生物转化生产生物燃料和化学品研究工作。围绕着木质纤维素原料的清洁综合利用,从原料的清洁预处理与组分分离、纤维素的酶催化水解、木质素的表征与利用等方面展开研究,通过采用化学、化工、生物、材料等学科的研究方法和表征手段,结合工程应用开发和基础原理解析,研究木质纤维素清洁转化的工艺与机理。主要研究方向包括以下几个方面:

n   木质纤维素清洁分级预处理技术及机理;

n   木质纤维素抗生物降解屏障的分子机制,原料结构特性对纤维素酶催化水解的影响机制;

n   纤维素酶催化水解的过程强化;

n   木质纤维素水解液生产微生物油脂的工艺技术和过程调控;

n   木素产品的表征与应用;

n   生物质转化过程的模拟与优化

n   直接生物质燃料电池开发

 

    基于以上研究工作,已在国内外期刊和会议上发表论文80余篇, 其中SCI收录60余篇,总引用超过3000次, H指数27Google学术引用统计);作为主编之一出版中、英文专著各一部;申请发明专利20项,PCT专利3项,其中10项已获中国专利授权。

 

近五年主要专著和论文

专著或章节

n  Chenyu Du, Xuebing Zhao, Dehua Liu, Carol Sze Ki Lin, Karen Wilson, Rafa Luque, James Clark. Introduction: an overview of biofuels and production technologies. In: R. Luque, CSK Lin, K Wilson and J. Clark (Eds), Handbook of Biofuels Production (2nd edition), Elsevier B.V, 2016.

n  Xuebing Zhao, Wei Liu, Yulin Deng, J.Y. Zhu*. Lignocellulosic Biomass-Energized Fuel Cells. Momentum Press, 2015.

n  Xuebing Zhao*, Feng Qi, Dehua Liu. Hierarchy Nano-and Ultrastructure of Lignocellulose and Its Impact on the Bioconversion of Cellulose. In: Mahendra Rai and Silvio Silvério da Silva (Eds), Nanotechnology for Bioenergy and Biofuel Production, Springer International Publishing, 2017, pp 117-151 (Invited book chapter)

n  陆强赵雪冰郑宗明. 液体生物燃料技术与工程. 上海上海科学技术出版社2013.1

期刊论文

Google Scholar Publication List:

http://scholar.google.com/citations?user=9PFjvSkAAAAJ&hl=en

2017

n  Junyang Wang, Xuebing Zhao*, Dehua Liu. Preparation of epoxidized fatty acid methyl ester with in situ auto-catalyzed generation of performic acid and the influence of impurities on epoxidation. Waste and Biomass Valorization, 2017 doi:10.1007/s12649-017-9945-6.

n  Tian Li, Qi Fang, Hongmei Chen, Feng Qi, Xianjin Ou, Xuebing Zhao*, Dehua Liu. Solvent-based delignification and decrystallization of wheat straw for efficient enzymatic hydrolysis of cellulose and ethanol production with low cellulase loadings. RSC Advances, 2017, 7, 10609-0617.

n  Xuebing Zhao*, Siming Li, Ruchun Wu, Dehua Liu. Organosolv fractionating pretreatment of lignocellulosic biomass for efficient enzymatic saccharification: chemistry, kinetics and substrate structures. Biofuels, Bioproducts and Biorefining. DOI: 10.1002/bbb.1768

n  Yi Ding, Bo Du, Xuebing Zhao*, J.Y. Zhu, Dehua Liu. Phosphomolybdic acid and ferric iron as efficient electron mediators for coupling biomass pretreatment to produce bioethanol and electricity generation from wheat straw. Bioresource Technology, 2017, 228:279–289 (Cover paper).

n  Xuebing Zhao, Wei Liu, Yulin Deng*, J.Y. Zhu*. Low-temperature Microbial and Direct Conversion of Lignocellulosic Biomass to Electricity: Advances and Challenges. Renewable & Sustainable Energy Reviews, 2017, 71: 268-282. DOI: 10.1016/j.rser.2016.12.055.

n  Xuebing Zhao*, Yi Ding, Bo Du, J.Y. Zhu, Dehua Liu. Polyoxometalate- mediated lignin oxidation for efficient enzymatic production of sugars and generation of electricity from lignocellulosic biomass. Energy Technology, 2017, DOI: 10.1002/ente.201600662.

2016

n  Hongmei Chen, Xuebing Zhao*, Dehua Liu. Relative significance of the negative impacts of hemicelluloses on enzymatic cellulose hydrolysis is dependent on lignin content: evidences from substrate structural features and protein adsorption ACS Sustainable Chemistry & Engineering, 2016, 4 (12): 6668–6679

n  Ardak Akimkulova, Yan Zhou, Xuebing Zhao*, Dehua Liu. Improving the enzymatic hydrolysis of dilute acid pretreated wheat straw by metal ion blocking of non-productive cellulase adsorption on lignin. Bioresource Technology, 2016, 208:110-116.

n  Ruchun Wu, Xuebing Zhao*, Dehua Liu. Structural features of Formiline pretreated sugarcane bagasse and their impacts on the enzymatic digestibility of cellulose. ACS Sustainable Chemistry & Engineering, 2016, 4 (3):1255–1261

n  Xuebing Zhao, J.Y. Zhu*, Efficient Conversion of Lignin to Electricity Using A Novel Direct Biomass Fuel Cell Mediated by Polyoxometalates at Low Temperatures. ChemSusChem 2016, 9(2): 197–207.

2015

n  Zhou Yan, Zhao Xuebing*, Liu Dehua. Effects of Non-ionic Surfactants on the Enzymatic Hydrolysis of Lignocellulose and Corresponding Mechanism. Progress in Chemistry 2015, 27(11): 1555-1565.

n  Yuanman Zhang, Ji’an Luo, Xuebing Zhao*, Dehua Liu**. A novel strategy for 1, 3-propanediol recovery from fermentation broth and colority control using scraped thin-film evaporation for desalination. RSC Advances 2015, 5:48269 - 48274

n  Hongmei Chen, Tianhang Hu, Jia Zhao, Xuebing Zhao*, Dehua Liu. A comparison of several organosolv pretreatments for increasing the enzymatic hydrolysis of wheat straw: substrate digestibility, fermentability and structural features. Applied Energy, 2015,150:224-232

n  Yan Zhou, Hongmei Chen, Feng Qi, Xuebing Zhao*, Dehua Liu. Non-ionic surfactants do not consistently improve the enzymatic hydrolysis of pure cellulose. Bioresource Technology, 2015, 182:136-143

n  Lei Dong, Xuebing Zhao *, Dehua Liu. Kinetic modeling of atmospheric formic acid pretreatment of wheat straw with “potential degree of reaction” models. RSC Advances 2015, 5:20992 – 21000, DOI: 10.1039/C4RA14634D

n  Xuebing Zhao*, Feng Qi, Chongli Yuan, Wei Du, Dehua Liu**. Lipase-catalyzed Process for Biodiesel Production: Enzyme Immobilization, Process Simulation and Optimization. Renewable & Sustainable Energy Reviews, 2015, 44: 182-197.

2014

n  Yuichi Morikawa, Xuebing Zhao*, Dehua Liu. Biological co-production of biodiesel and ethanol from wheat straw: A case of dilute acid pretreatment. RSC Advance, 2014, 4:37878-37888, DOI: 10.1039/c4ra07251k.

n  Qianqian Wang, Xuebing Zhao*, J.Y. Zhu**. Kinetics of Strong Acid Hydrolysis of A Bleached Kraft Pulp for Producing Cellulose Nanocrystals (CNC). Industrial & Engineering Chemistry Research, 2014, 53 (27): 11007–11014 DOI: 10.1021/ie501672m

n  Xingkai Cui, Xuebing Zhao*, Jing Zeng, Soh Kheang Loh, Yuen May Choo, Dehua Liu. Robust enzymatic hydrolysis of Formiline-pretreated oil palm empty fruit bunches (EFB) for efficient conversion of polysaccharide to sugars and ethanol. Bioresource Technology, 2014, 166: 584–591. DOI: 10.1016/j.biortech.2014.05.102

n  Feng Qi, Yuki Kitahara, Zitian Wang, Xuebing Zhao, Wei Du, Dehua Liu. Novel mutant strains of Rhodosporidium toruloides by plasma mutagenesis approach and their tolerance for inhibitors in lignocellulosic hydrolyzate. Journal of Chemical Technology & Biotechnology, 2014, 89(5): 735-742.

n  Xuebing Zhao*, Yuichi Morikawa, Feng Qi, Jing Zeng, Dehua Liu. A novel kinetic model for polysaccharide dissolution during atmospheric acetic acid pretreatment of sugarcane bagasse. Bioresource Technology 2014, 151: 128–136.

n  Hyun Tae Hwang, Feng Qi, Chongli Yuan, Xuebing Zhao*, Doraiswami Ramkrishna1, Dehua Liu and Arvind Varma*. Lipase-Catalyzed Process for Biodiesel Production: Protein engineering and lipase production. Biotechnology & Bioengineering, 2014, 111(4):639-653.

2013

n  Xuebing Zhao*, Ming Fan, Jing Zeng, Wei Du, Canming Liu, Dehua Liu. Kinetics of lipase recovery from the aqueous phase of biodiesel production by macroporous resin adsorption and reuse of the adsorbed lipase for biodiesel preparation. Enzyme and Microbial Technology, 2013, 52(4-5): 226-233.

n  Lu He, Xuebing Zhao*, Keke Cheng, Yan Sun, Dehua Liu**. Kinetic modeling of fermentative production of 1, 3-propanediol by Klebsiella pneumoniae HR526 with consideration of multiple product inhibitions. Applied Biochemistry and Biotechnology, 2013, 169(1): 312-326.

n  Xuebing Zhao*, Dehua Liu. Kinetic modeling and mechanisms of acid-catalyzed delignification of sugarcane bagasse by aqueous acetic acid. BioEnergy Research, 2013, 6(2): 436-447.

n  Xuebing Zhao*, Lei Dong, Liang Chen, Dehua Liu. Batch and multi-step fed-batch enzymatic saccharification of Formiline-pretreated sugarcane bagasse at high solid loadings for high sugar and ethanol titers. Bioresource Technology, 2013, 135:350-356

2012

n  Yuanquang Song, Qiang Li, Xuebing Zhao*, Yan Sun, Dehua Liu**. Production of 2,3-butanediol by Klebsiella pneumoniae from enzymatic hydrolyzate of sugarcane bagasse. BioResources, 2012, 7(4), 4517-4530.

n  Xuebing Zhao*, Dehua Liu. Fractionating pretreatment of sugarcane bagasse by aqueous formic acid with direct recycle of spent liquor to increase cellulose digestibility-the Formiline process. Bioresource Technology, 2012, 117: 25-32.

n  Xuebing Zhao*, Lihua Zhang, Dehua Liu. Biomass recalcitrance, Part II: fundamentals of different pretreatments to increase the enzymatic digestibility of lignocellulose. Biofuels, Biorproducts and Biorefinery, 2012, 6(5): 561-579.

n  Xuebing Zhao*, Lihua Zhang, Dehua Liu. Biomass recalcitrance, Part I: the chemical compositions and physical structures affecting the enzymatic hydrolysis of lignocellulose. Biofuels, Biorproducts and Biorefinery, 2012, 6(4): 465-482.

n  Xuebing Zhao*, Yujie Zhou, Dehua Liu. Kinetic model for glycan hydrolysis and formation of monosaccharides during dilute acid hydrolysis of sugarcane bagasse. Bioresource Technology, 2012, 105: 160-168.

n  Xuebing Zhao*, Feng Peng, Wei Du, Canming Liu, Dehua Liu. Effects of some inhibitors on the growth and lipid accumulation of oleaginous yeast Rhodosporidium toruloides and preparation of biodiesel by enzymatic transesterification of the lipid. Bioprocess and Biosystems Engineering, 2012, 35(6): 993-1004.

(* and ** indicate that the author(s) is (are) corresponding author)