戈钧

博士,特别研究员,博士生导师

清华大学化工系生物化工研究所

工业生物催化教育部重点实验室

地址:北京市清华大学英士楼108

邮编:100084

电话:+86-10-62780775

Email:  junge@mail.tsinghua.edu.cn

 

教育和工作经历

2000-2004年,清华大学,化工系,高分子材料专业,学士

2004-2009年,清华大学,化工系,生物化工专业,博士

2009-2012年,斯坦福大学,化学系,博士后

20121-201212月,清华大学,化工系,讲师

201212-20168月,清华大学,化工系,副教授,博士生导师

20169月至今,清华大学,化工系,特别研究员,博士生导师

 

研究方向:酶固定化/化学修饰,工业生物催化,生物传感器

从事酶固定化方法及其在工业生物催化和生物传感器领域的应用研究。作为项目负责人主持国家自然科学基金优秀青年基金、国家重点研发计划纳米科技重点专项青年科学家项目、生物与医药领域863计划青年科学家专题等项目。研究工作发表论文40余篇,部分论文发表在Nature Nanotechnology, Nano Letters, ACS Nano, ACS Catalysis等期刊。2015年入选MIT Technology Review评选的World 35 Innovators Under 35

代表论文

Zhang, C.; Wang, X.; Hou, M.; Li, X.; Wu, X.; Ge, J.* Immobilization on metal-organic framework engenders high sensitivity for enzymatic electrochemical detection. ACS Applied Materials & Interfaces 2017, DOI: 10.1021/acsami.7b02803

Wu, X.; Ou, G.; Yang, C.; Ge, J.*, Wu, H.* Enhanced enzymatic reactions by solar-to-thermal conversion nanoparticles. Chemical Communications 2017, DOI: 10.1039/C7CC01522D

Li, Z.; Ding, Y.; Li, S.; Jiang, Y.*; Liu, Z.; Ge, J.* Highly active, stable and self-antimicrobial enzyme catalysts prepared by biomimetic mineralization of copper hydroxysulfate. Nanoscale 2016, 8, 17440-17445.

Wu, X.; Yang, C.; Ge, J.*; Liu, Z. Polydopamine tethered enzyme/metal-organic framework composites with high stability and reusability. Nanoscale 2015, 7, 18883-18886. (Featured on the Cover)

Wu, X.; Hou, M.; Ge, J.* Metal-organic frameworks and inorganic nanoflowers: a type of emerging inorganic crystal nanocarriers for enzyme immobilization. Catalysis Science & Technology 2015, 5, 5077-5085. (Invited Review)

Zhang, Y.; Ge, J.*; Liu, Z.* Enhanced activity of immobilized or chemically modified enzymes. ACS Catalysis 2015, 5, 4503-4513. (Invited Review)

Wu, X.; Ge, J.*; Yang C.; Hou, M.; Liu, Z. Facile synthesis of multiple enzyme-containing metal-organic frameworks in a biomolecule-friendly environment. Chemical Communications 2015, 51, 13408-13411.

Wu, X.; Ge, J.*; Zhu, J.; Zhang, Y.; Yong, Y.; Liu, Z.* A general method for synthesizing enzyme-polymer conjugates in reverse emulsions using Pluronic as a reactive surfactant. Chemical Communications 2015, 51, 9674-9677.

Lyu, F.; Zhang, Y.; Zare, R. N.; Ge, J.*; Liu, Z.* One-pot synthesis of protein-embedded metal-organic frameworks with enhanced biological activities. Nano Letters 2014, 14, 5761-5765.

Li, Z.; Zhang, Y.; Su, Y.; Ouyang, P.; Ge, J.*; Liu, Z.* Spatial co-localization of multi-enzymes by inorganic nanocrystal-protein complexes. Chemical Communications 2014, 50, 12465-12468.

Zhang, Y.; Lyu, F.; Ge, J.*; Liu, Z.* Ink-jet printing an optimal multi-enzyme system. Chemical Communications 2014, 50, 12919-12922.

Zhang, Y.; Chen, Q.; Ge, J.*; Liu, Z.* Controlled display of enzyme activity with a stretchable hydrogel. Chemical Communications 2013, 49, 9815-9817.

Zhu, J.; Zhang, Y.; Lu, D.; Zare, R. N.; Ge, J.*; Liu, Z.* Temperature-responsive enzyme-polymer nanoconjugates with enhanced catalytic activities in organic media. Chemical Communications 2013, 49, 6090-6092.

Wang, R.; Zhang, Y.; Huang, J.; Lu, D.; Ge, J.*; Liu, Z.* Substrate imprinted lipase nanogel for one-step synthesis of chloramphenicol palmitate. Green Chemistry 2013, 15, 1155-1158.

Ge, J.; Lei, J.; Zare, R. N.* Protein-inorganic hybrid nanoflowers. Nature Nanotechnology 2012, 7, 428-432. (Featured on the Cover, Highlighted by Science, Nature Nanotechnology, and The Scientist)

Ge, J.; Neofytou, E.; Lei, J.; Beygui, R. E.; Zare, R. N.* Protein-polymer hybrid nanoparticles for drug delivery. Small 2012, 8, 3573-3578.

Ge, J.; Neofytou, E.; Cahill, III, T. J.; Beygui, R. E.; Zare, R. N.* Drug release from electric-field-responsive nanoparticles. ACS Nano 2012, 6, 227-233. (Highlighted by Chemical&Engineering News, ACS Nano, Nanomedicine)

Ge, J.; Lei, J. D.; Zare, R. N.* Bovine serum albumin-poly(methyl methacrylate) nanoparticles: an example of frustrated phase separation. Nano Letters 2011, 11, 2551-2554. (Highlighted by Science)

Ge, J.; Jacobson, G. B.; Lobovkina, T.; Holmberg, K.; Zare, R. N.* Sustained release of nucleic acids from polymeric nanoparticles using microemulsion precipitation in supercritical carbon dioxide. Chemical Communications 2010, 46, 9034-9036.

Ge, J.; Lu, D.; Wang, J.; Liu, Z.* Lipase nanogel catalyzed transesterification in anhydrous dimethyl sulfoxide. Biomacromolecules 2009, 10, 1612-1618.

Ge, J.; Lu, D.; Wang, J.; Yan, M.; Lu, Y.*; Liu, Z.* Molecular fundamentals of enzyme nanogels. Journal of Physical Chemistry B 2008, 112, 14319-14324.