戈钧

博士,长聘副教授

清华大学化学工程系

地址:北京市清华大学英士楼

邮编:100084

电话:+86-10-62780775

Email:  junge@mail.tsinghua.edu.cn

 

Jun Ge, Ph.D.

Associate Professor

Department of Chemical Engineering

Tsinghua University, Beijing 100084

Tel: +86-10-62780775

Email: junge@mail.tsinghua.edu.cn

 

 

 

  戈钧,清华大学化学工程系长聘副教授,博士生导师。于2004年,2009年在清华大学化学工程系获得本科和博士学位,2009年至2012年在斯坦福大学化学系进行博士后研究,2012年开始在清华大学化学工程系工作。主要从事酶催化剂工程及其在生物催化、生物传感以及生物医学等领域的应用研究。研究工作累计发表SCI论文60余篇,部分论文发表在Nature Nanotechnology, Nature Catalysis, Nature Communications, Science Advances, Nano Letters, ACS Nano, ACS Catalysis等期刊。获得国家优青,北京市杰青,国家重点研发计划青年项目,863生物医药领域青年科学家专题等资助,入选长江学者奖励计划青年学者。获得MIT Technology Review World 35 Innovators Under 35闵恩泽能源化工奖青年进步奖。

 

  Dr. Jun Ge received his B.Sc. and Ph.D. from the Department of Chemical Engineering, Tsinghua University in 2004 and 2009. From 2009 to 2012, Dr. Ge did his postdoc in the Department of Chemistry, Stanford University. Dr. Ge is now an associate professor in the Department of Chemical Engineering, Tsinghua University. His research interests include nanobiotechnology, enzyme immobilization, enzymatic catalysis, biosensing and biomedicine. Prof. Ge has published over 60 papers in scientific journals, including Nature Nanotechnology, Nature Catalysis, Nature Communications, Science Advances, Nano Letters, ACS Nano, ACS Catalysis. Dr. Ge was selected as the member of MIT Technology Review World 35 Innovators Under 35 in 2015.

 

教育和工作经历

Education and Professional Backgrounds

 

2000-2004年,清华大学,化工系,高分子材料专业,学士

2004-2009年,清华大学,化工系,生物化工专业,博士

2009-2012年,斯坦福大学,化学系,博士后

20121-201212月,清华大学,化工系,讲师

201212-20177月,清华大学,化工系,副教授,博士生导师

20178月至今,清华大学,化工系,长聘副教授,博士生导师

 

2000~2004   B.Sc, Department of Chemical Engineering, Tsinghua University

2004~2009   Ph.D, Department of Chemical Engineering, Tsinghua University

2009~2012   Postdoctoral Scholar, Department of Chemistry, Stanford University

2012      Assistant Professor, Department of Chemical Engineering, Tsinghua University

2012~   Associate Professor, Department of Chemical Engineering, Tsinghua University

 

研究领域

Research Interests

 

酶催化、纳米生物技术、生物传感、生物医药

Enzymatic catalysis, Nanobiotechnology, Biosensing, Biomedicine

 

 

代表性论文

Selected publications

 

1)        Hu, C.#; Bai, Y.#; Hou, M.; Wang, Y.; Wang, L.; Cao, X.; Chan, C.-W.; Sun, H.; Li, W.; Ge, J.*; Ren, K.*. Defect-induced activity enhancement of enzyme-encapsulated metal-organic frameworks revealed in microfluidic gradient mixing synthesis. Sci. Adv. 2020, 6, eaax5785.

2)        Wu, X.#; Yue, H.#; Zhang, Y.#; Gao, X.; Li, X.; Wang, L.; Cao, Y.; Hou, M.; An, H.; Gu, H.; Zhang, L.*; Li, S.*; Lou, W.; Ma, J.; Lin, H.; Fu, Y.; Wei, W.*; Zare, R. N.; Ge, J.* Packaging and delivering enzymes by amorphous metal-organic frameworks. Nat. Commun. 2019, 10, 5165.

3)        Li, X.#; Cao, Y.#; Luo, K.#; Sun, Y.; Xiong, J.; Wang, L.; Liu, Z.; Li, J.; Ma, J.; Ge, J. *; Xiao, H. *; Zare, R. N. * Highly active enzyme-metal nanohybrids synthesized in protein-polymer conjugates. Nat. Catal. 2019, 2, 718-725.

4)        Li, X.; Cao, X.; Xiong, J.; Ge, J.* Enzyme-metal hybrid catalysts for chemoenzymatic reactions. Small 2019, DOI: 10.1002/smll.201902751

5)        Cao, Y.#; Li, X.#; Xiong, J.; Wang, L.; Yan, L.*; Ge, J.* Investigating the origin of high efficiency in confined multienzyme catalysis. Nanoscale, 2019, 11, 22108-22117.

6)        Zhang, C.; Wang, X.; Hou, M.; Li, X.; Wu, X.; Ge, J.* Immobilization on metal-organic framework engenders high sensitivity for enzymatic electrochemical detection. ACS Applied Materials & Interfaces 2017, 9, 13831-13836.

7)        Wu, X.#; Ou, G.#; Yang, C.; Ge, J.*, Wu, H.* Enhanced enzymatic reactions by solar-to-thermal conversion nanoparticles. Chemical Communications 2017, 53, 5048-5051.

8)        Zhang, Y.; Ge, J.*; Liu, Z.* Enhanced activity of immobilized or chemically modified enzymes. ACS Catalysis 2015, 5, 4503-4513.

9)        Wu, X.; Hou, M.; Ge, J.* Metal-organic frameworks and inorganic nanoflowers: a type of emerging inorganic crystal nanocarriers for enzyme immobilization. Catalysis Science & Technology 2015, 5, 5077-5085.

10)    Wu, X.; Yang, C.; Ge, J.*; Liu, Z. Polydopamine tethered enzyme/metal-organic framework composites with high stability and reusability. Nanoscale 2015, 7, 18883-18886.

11)    Wu, X.; Ge, J.*; Yang C.; Hou, M.; Liu, Z. Facile synthesis of multiple enzyme-containing metal-organic frameworks in a biomolecule-friendly environment. Chemical Communications 2015, 51, 13408-13411.

12)    Lyu, F.; Zhang, Y.; Zare, R. N.; Ge, J.*; Liu, Z.* One-pot synthesis of protein-embedded metal-organic frameworks with enhanced biological activities. Nano Lett. 2014, 14, 5761-5765.

13)    Ge, J.#; Neofytou, E.#; Lei, J.; Beygui, R. E.; Zare, R. N.* Protein-polymer hybrid nanoparticles for drug delivery. Small 2012, 8, 3573-3578.

14)    Ge, J. #; Neofytou, E. #; Cahill, III, T. J.; Beygui, R. E.; Zare, R. N.* Drug release from electric-field-responsive nanoparticles. ACS Nano 2012, 6, 227-233.

15)    Ge, J.#; Lei, J.#; Zare, R. N.* Protein-inorganic hybrid nanoflowers. Nat. Nanotech. 2012, 7, 428-432.

16)    Ge, J.; Lei, J. D.; Zare, R. N.* Bovine serum albumin-poly(methyl methacrylate) nanoparticles: an example of frustrated phase separation. Nano Letters 2011, 11, 2551-2554.